Regulatory expression of Co-inhibitory receptors by Type 1 Interferon transcriptional network in human T cells
Rohit Bhattacharjee, Amity University Kolkata Although inhibition of T cell co-inhibitory receptors has brought about cancer therapy, mechanisms governing their expression on human T cells have not been explained. Type 1 interferon (IFN-I) regulates T cell immunity in viral infection, autoimmunity, cancer, and may enhance induction of T cell exhaustion in chronic viral infection. To […]