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May 12, 2025
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Tag: RNA

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Extracellular vesicles for shuttling small RNAs and proteins

bioxone June 29, 2021June 29, 2021 1

Aparna Pandey, IILM Academy of Higher learning and Education, Greater Noida Extracellular vesicles are small sheaths particles derived from various cell types. Extracellular vesicles are lipid bilayer-enclosed, cytosol-containing spheres that are liberated by all eukaryotes and prokaryotic cells into the extracellular environment. Small RNAs plays an important role in different cellular processes like differentiation in […]

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CDK9: A Key regulator of RNA Polymerase II Transcription

bioxone June 24, 2021June 23, 2021 1

Shayan Ahmed, Jamia Millia Islamia, New Delhi It has been discovered that Cyclin-Dependent Kinase 9 (CDK9) is an important regulator of RNA Polymerase II transcription. As a regulator CDK9 works across the transcription unit at multiple locations. These include the transcriptional pause release before elongation by the action of positive transcription elongation factor b (P-TEFb). […]

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Drug development from traditional to recent methods

bioxone June 7, 2021June 7, 2021 2

Varuni Ankolekar, Clinical Data Manager Traditionally, the discovery of drugs was done by recognizing the active ingredients from traditional remedies or unexpectedly.  Later, Scientists discovered that the interaction of specific chemicals in the drug with biological molecules of the human body serves the purpose of the drug. Later, Chemical pharmacological approaches were made to identify […]

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EF-TU: Travel back in time and evolve with this special protein!!!

bioxone May 7, 2021May 7, 2021 1

Anannya Roy, Amity University Kolkata One of the main functions a cell performs is the synthesis of proteins. This is done with the help of a set of factors called “transcription factors”. A team of researchers from Uppasala University have succeeded in studying transcription factors that are several billion years old. The studies helped them […]

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X10-23 reagent improves the activity of DNAzymes!

bioxone April 3, 2021April 3, 2021 2

Devyani Goswami, Amity University Kolkata DNAzymes area type of DNA catalysts. DNAzymes are known for their specialty in catalyzing site-specific cleavage of any RNA substrate. RNA-cleaving DNA enzyme has a catalytic core and two short binding arms which form Watson and Crick base pairs with the RNA targets. RNA cleavage is possible with the assistance […]

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Hovlinc: a new class of ribozyme

bioxone March 30, 2021March 30, 2021 1

Shagufta Hasan, Amity University Catalytic RNA, Ribozymes, found in the ribosomes form polypeptide chains by linking amino acids together. The RNA enzyme catalyzes a chemical reaction in a similar way to that of protein enzymes. They also participate in processes like RNA splicing, viral replication etc. Although they have attracted a great deal of research […]

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SGL: Hidden part in Bacteriophages could be a Protein Antibiotic

bioxone March 18, 2021March 18, 2021 1

Ayooshi Mitra, Amity University, Kolkata Antibiotic-resistant bacteria are becoming a greater threat to human health day by day, necessitating the development of new antibiotics. Bacteriophages and their potential as antibacterial agents to combat pathogenic bacteria have sparked renewed interest. This is largely due to the phage’s ability to cause a cellular breakdown in the bacterial […]

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SARS-CoV-2: CAN INCORPORATE THEIR GENOME IN THE HOST CELL

bioxone February 25, 2021February 25, 2021 1

PRAGYA SANTRA, AMITY UNIVERSITY COVID-19 drastically hit 2020, an eye-witnessed pandemic for us all. Analysis from many patients suffering from COVID-19 the second time suggests that the immune system failed to ward off the second thrash of the virus. A recent study now puts light on the fact. Reports highlight that the coronavirus mutates itself […]

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Main protease enzyme of SARS CoV-2 against COVID-19

bioxone January 21, 2021January 21, 2021 1

-Rohit Bhattacharjee, Amity University Kolkata Coronavirus 2019 – the episode is a worldwide pandemic brought about by (SARS-CoV-2) which at first analyzed in Chinese patients of Hubei’s Wuhan city toward the beginning of December 2019. COVID-19 has been proclaimed a worldwide wellbeing catastrophe by World Health Organization (WHO) as the illness quickly communicated human-to-human and […]

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DRY SWAB-DIRECT RT-PCR TO RAMP UP TEST FREQUENCY

bioxone December 3, 2020December 3, 2020 1

RUCHITA KARMAKAR, AMITY UNIVERSITY KOLKATA The Indian Council of Medical Research (ICMR) agreed a dry swab-direct RT-PCR testing method for the COVID-19 virus which is presently developed by CSIR-Centre for Cellular and Molecular Biology (CCMB). This new method of dry swab-direct test aimed at ascending the test by atleast two to three folds with no […]

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Breaking News

The Corrosion Prediction from the Corrosion Product Performance

Nitrogen Resilience in Waterlogged Soybean plants

Cell Senescence in Type II Diabetes: Therapeutic Potential

Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP

AI Literacy in Early Childhood Education: Challenges and Opportunities

Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

Exogenous Klotho as a Cognition Booster in Aging Primates

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