Tholkappian R, NIT Durgapur Nirmatrelvir is an oral inhibitor of the SARS-CoV-2’s, 3-chymotrypsin–like cysteine protease, while VV116 is a deuterated remdesivir hydro-bromide with potent activity against SARS-CoV-2. Nirmatrelvir-ritonavir was used to treat COVID-19 of low to moderate severity. However, its production could not meet the global supply demands. VV116 is one such oral analog of […]
Aayushi Gaur, U. I. E. T., Kurukshetra University Doctors battled to keep patients breathing in the early months of the COVID-19 pandemic, focusing mostly on treating lung and circulatory system damage. However, evidence of neurological consequences was already collecting at the time. Some COVID-19 patients were suffering from delirium, which manifested as confusion, disorientation, and […]
Sneha Singhal, Jaypee Institute of information technology, Noida Pfizer Inc. and Merck & Co. in the race to find treatments for Covid-19 have joined a Japanese company in starting human trials for the first once-daily pill. Shionogi and Co., of Osaka, claimed that its pill would neutralize the Coronavirus in five days or less. The […]
Saptaparna Pal, Amity University Kolkata The Union Health Ministry’s Directorate General of Health Sciences (DGHS) has proposed revised Covid-19 guidelines and removed all medicines except antipyretic (fever) and antitussive (cold) for mild and asymptomatic cases. The revised Covid-19 guidelines issued on 27 May 2021 dropped all medicines that the doctors have been prescribing even to […]
Parnad Basu, Amity University Kolkata Remdesivir (C27H35N6O8P), is a broad-spectrum antiviral medication. It is administered via injection into a vein. Before the completion of clinical trials of the COVID-19 vaccines, remdesivir will be used to fight COVID-19. Now, COVID-19 is always mutating. And it is important to study those mutations to make remdesivir more effective […]
Sayak Banerjee. Amity University Kolkata Scientists at Washington State University (WSU) discovered that other than immune cells, neutrophils also might play a major role in defense against infection, through a new drug delivery technology. Neutrophils are the most common type of white blood cells (WBCs) that lead the body’s immune system response. They established a […]
Souradip Mallick, National Institute of Technology, Rourkela The emergence of SARS-CoV-2 virus has resulted in a worldwide pandemic killed over 1,368,000 people globally (WHO). Currently, effective treatments to inhibit SARS-CoV-2 morbidity and mortality are not available. The pharmacological screen identified several compounds capable of blocking the in vitro replication of two beta-coronaviruses. Among many ones […]
