Sayak Banerjee, Amity University Kolkata Nerve agents, also known as nerve gases, belong to a class of organic chemicals that interrupts the nerves from transferring messages to organs. This interruption takes place due to the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of the neurotransmitter, acetylcholine. So basically nerve agents are AChE […]
Camelia Bhattacharyya, Amity University Kolkata Charlotte Brontë, the famous British novelist of the 19th century once said, “A ruffled mind makes a restless pillow.” Reading this today tells us how ahead of time a novelist’s thought process can be. This line clearly explains the causes and effects of insomnia. It is caused mostly due to […]
Shinjini Bandopadhyay, Amity University Kolkata ORIGIN AND UNDERSTANDING OF PHANTOM LIMB PAIN Phantom Limb Pain (PLP) is the pain associated with a missing or amputated limb. Severe trauma, tumor, vascular diseases, or infections can result in surgical removal or amputation of a limb, giving rise to phantom limb sensations of excruciating pain or discomfort in […]
Surupa Chakraborty, Amity University Kolkata A new gene therapy clinical trial for treating Angelman syndrome has been put to hold after two candidates temporarily lost their ability to walk. GTX102, the drug used in the clinical trial was developed by a California-based biopharmaceutical company Ultragenyx, in collaboration with GeneTx, a Florida-based biotech startup. The trial […]
Saptaparna Pal, Amity University Kolkata Axons of the adult peripheral nervous system(PNS) and immature central nervous system (CNS) neurons readily regenerate after injury. In addition to the non-permissive extracellular environment after injury, the intrinsic neuronal factors also play an important role in the regenerative failure that is observed in mature CNS neurons. Protrudin acts as […]
-Shrayana Ghosh, Amity University A recent study conducted at Yale University compared the immune system cells in the spinal fluid of healthy people and people with Multiple Sclerosis (MS). It was reported that an inflammatory autoimmune response within the CNS (Central Nervous System) has been identified that is associated with neurodegenerative disorders such as MS. […]
– Sagnik Nag, Amity University Kolkata Cerebrospinal fluid (CSF) protects the CNS from physical injuries as well as portrays immuno-surveillance over a pathogenic attack. In recent scientific research conducted by Pappalardo et al. profiled the T-cells present in the cerebrospinal fluid (CSF) of a healthy individual. It is known that T-cells ( be it CD4+ or […]
