Why do we age? Discover the biology behind ageing, from DNA damage and genomic instability to the Hallmarks of Ageing. Explore the science shaping modern longevity research in the first article of BioXone’s DNA Mysteries series.
Snata Pandey, St. Xavier’s College (Autonomous), Kolkata The dark side of cell cycle Cell senescence is a permanent arrest of the cycle of a damaged or stressed cell, at either the gap 1 (G1) or the gap 2 (G2) phase. Senescence starts during embryogenesis, occurs throughout life, but senescent cells are regularly cleared by the […]
Vaishnavi Kardale, Bioinformatics Centre, Savitribai Phule Pune University For a very long time, researchers have been searching for ways to increase human life. In this quest, they have found one promising protein -mTOR. The finding of mTOR has given rise to a whole field in cellular biology that studies mTOR and its associated pathway. mTOR- […]
Akash Singh, Banaras Hindu University Autophagy, often blamed for senescence, is a conserved process that promotes cellular homeostasis by degrading cytosolic components (sometimes referred to as cargo). This cargo sequestered into autophagosomes, which are double-membrane vesicles that are primarily carried in the retrograde direction to the perinuclear area, where they combine with lysosomes, ensuring cargo […]
Aakancha Shaw, St. Xavier’s College, Kolkata According to new research conducted by the University of East Anglia (UEA), fasting could impact the health of future generations in a significant manner. Fasting diets have become a trend nowadays and have gained popularity in recent years. However, the long term impact of this reduced intake of food […]
-Priyanka Chakraborty, Amity University Kolkata It was established that stem cells present in hair follicle reside in low oxygen availability and hence uses glucose rather than glutamine metabolism as a source of energy. This shift is perpetually done by Rictor signalling and oxygen concentration. Stem cells can be developed accordingly to prevent Hair loss. Hair […]
