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A unique class of T cells may improve immunotherapeutic treatments

Synthetic brain cell, to identify the transformation of viruses
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Synthetic brain cell, to identify the transformation of viruses

bioxone September 26, 2020September 26, 2020

Sambit Majumdar, Amity University Kolkata

Researchers of Texas A&M University, Hewlett Packard Labs, and Stanford University have discovered a new nanodevice that is almost like a brain. 

Dr. Stanley Williams, professor of electrical and computer engineering said that this is the first study by them, where they have been able to surpass a neuron with just a single nanoscale device, instead of hundreds of transistors. In these, the researcher particularly reveals proof of concept that their brain-inspired system can identify a possible mutation in a virus, which is highly relevant for ensuring the efficiency of vaccines and medication for strain exhibiting genetic diversity. 

This synthetic nanoscale device consisting of layers of different inorganic materials each have a distinctive purpose to build a block of the brain or neuron, this all happens in the thin layer of compound niobium dioxide. On applying minimum voltage, its temperature starts to increase and reaches a critical value and the compound shows a quick response in personality turning from insulator to a conductor. As it conducts electric currents, its temperature drops and the compound returns to an insulator. Back and forth transition allows the synthetic device generates a pulse of electric current that forms electric spikes, produced by a biological neuron. 

They introduced the network to short gene fragments and formed basic rules for joining these genetic fragments. They found that within a microsecond a network of artificial neurons settles down in a state that was indicative of the genome for mutant strain.

Source: 

Kumar, S., Williams, R.S. & Wang, Z. Third-order nanocircuit elements for neuromorphic engineering. Nature585, 518–523 (2020). https://doi.org/10.1038/s41586-020-2735-5

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Tagged chaotic dynamics conductor element construction genetic fragments insulator neuromorphic engineering neuroscience Niobium dioxide synthetic brain cells synthetic nanoscale device Texas United States US US Texas virus detection

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A unique class of T cells may improve immunotherapeutic treatments

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