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A unique class of T cells may improve immunotherapeutic treatments

Synthetic brain cell, to identify the transformation of viruses
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Synthetic brain cell, to identify the transformation of viruses

bioxone September 26, 2020September 26, 2020

Sambit Majumdar, Amity University Kolkata

Researchers of Texas A&M University, Hewlett Packard Labs, and Stanford University have discovered a new nanodevice that is almost like a brain. 

Dr. Stanley Williams, professor of electrical and computer engineering said that this is the first study by them, where they have been able to surpass a neuron with just a single nanoscale device, instead of hundreds of transistors. In these, the researcher particularly reveals proof of concept that their brain-inspired system can identify a possible mutation in a virus, which is highly relevant for ensuring the efficiency of vaccines and medication for strain exhibiting genetic diversity. 

This synthetic nanoscale device consisting of layers of different inorganic materials each have a distinctive purpose to build a block of the brain or neuron, this all happens in the thin layer of compound niobium dioxide. On applying minimum voltage, its temperature starts to increase and reaches a critical value and the compound shows a quick response in personality turning from insulator to a conductor. As it conducts electric currents, its temperature drops and the compound returns to an insulator. Back and forth transition allows the synthetic device generates a pulse of electric current that forms electric spikes, produced by a biological neuron. 

They introduced the network to short gene fragments and formed basic rules for joining these genetic fragments. They found that within a microsecond a network of artificial neurons settles down in a state that was indicative of the genome for mutant strain.

Source: 

Kumar, S., Williams, R.S. & Wang, Z. Third-order nanocircuit elements for neuromorphic engineering. Nature585, 518–523 (2020). https://doi.org/10.1038/s41586-020-2735-5

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Tagged chaotic dynamics conductor element construction genetic fragments insulator neuromorphic engineering neuroscience Niobium dioxide synthetic brain cells synthetic nanoscale device Texas United States US US Texas virus detection

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A unique class of T cells may improve immunotherapeutic treatments

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-Binayak Das, Team Bioxone A new study has revealed the presence of a unique class of T cells, known as the Memory CD8 T lymphocytes, in mice, and its analogous population in humans also. This class of memory cells exhibited combined molecular functioning characteristic features, of both short-lived effector cells and long-lived memory T cells. […]

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Discovery of a better gene-editing tool?

bioxone October 23, 2020October 23, 2020

Shrayana Ghosh, Amity University Kolkata According to a new study by UC San Francisco scientists, gene editing for the generation of different treatments and the study of disease and normal function in humans and other organisms may develop more rapidly with a new tool for cutting larger pieces of DNA out of the genome of […]

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PurZ : A new virus genome on the block

bioxone May 17, 2021May 17, 2021

Thota Kanishka Rao, Amity University Kolkata A, C, T, and G are the four building blocks of DNA. However, some bacteriophage viruses use a particular DNA alphabet to encode their genetic instructions., i.e, exchange A for Z. Scientists in Russia announced more than 40 years ago that cyanophage S-2L, a form of bacteriophage, replaces the […]

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