Sagnik Nag, Amity University Kolkata
The emergence of an exceedingly pathogenic human Coronavirus in the Middle East has sparked novel concern in human coronaviruses around the world. Standing today we know all the precautions that are to be followed during this pandemic situation. The general symptoms about the outbreak of the Covid -19, but the specific treatment remains undiscovered. Precise experimental assays and research work are required to detect specific antibodies against SARS-CoV-2 to control the flaring pandemic of COVID -19.
According to the research conducted by Tiancheng Liu et. al. on human saliva and serum to detect the presence of antibodies against the S1 spike protein of the novel virus. It was an antibody and antibody-avidity assay depending upon near-infrared-fluorescence amplification by nanostructured plasmonic gold substrates. Furthermore, the experimental assay quantifies immunoglobulin avidities against SARS-CoV-2, SARS-CoV-1, and the common-cold viruses OC43, HKU1, NL63, and 229E.
The results for antibody assay detected immunoglobulins M and G in the serum collected at least 15 days after symptom onset and 82% of the samples i.e. 52 out of 60 had IgM upon 6 days after symptoms appeared. The antibody-avidity assay was done to check the cross-immunity to the common-cold coronaviruses and to study antibody maturation factors.
Also read: Eatable antibody factories to combat deadly gut infections!
Reference- https://link.researcher-app.com/HTTL
Amazing work Sagnik! Keep it up.