-Binayak Das, Team bioXone
A team of scientists claims that Indians should be grateful to their genetics, which according to their study is a critical factor in having a comparatively lesser number of deaths from COVID-19 in their populations. They studied the complete DNA data of the ACE2 gene in the X chromosomes from different continental populations. In their study published in PLOS ONE, the mention probable reasons for lower mortality rates were observed amongst Indian populations against US or European populations.
In their study, they conducted a haplotype-based analysis of the ACE2 gene, to study all of its possible genetic mutations in great depth. They found that certain mutations are possibly helping the South and East Asian populations by improving their resistance against the novel coronavirus, leading to a lower number of fatalities. The similarity in the DNA fragments between the South Asian and East Asian populations was found to be significantly similar, which might explain the lower mortality rate observed in both of these populations. They reported two major mutations of the ACE2 gene which were found to be responsible for improving the entry point of the virus, to be of key importance in establishing the resistance.
The team composed of Rudra Pandey and Prajwal Singh from BHU, Avinash Rasalkar, Pankaj Srivastava from Sagar Central University, Rakesh Tamang from Calcutta University and Pramod Kumar from National Centre for Disease Control (NCDC), Prof. George van Driem of University of Bern, Switzerland, and others believe that their study will help researchers to better understand the patterns of transmission of the deadly virus.
Source: Anshika Srivastava, Rudra Kumar Pandey, Pramod Kumar, Avinash Arvind Rasalkar, Rakesh Tamang, Pankaj Shrivastava, Gyaneshwer Chaubey, Most frequent South Asian haplotypes of ACE2 share identity by descent with East Eurasian populations, Evolutionary Genetics 10.21203/rs.3.rs-27310/v1 Link- https://www.researchsquare.com/article/rs-27310/v1
For more news please visit https://bioxone.in//
Another cause of Hepatocellular Carcinoma (HCC) apart from alcoholism
-Sristi Raj Rai, Amity University Kolkata Alcohol consumption is not always the cause of hepatocellular carcinoma (HCC). People who drink little or no amount of alcohol can also develop a symptomless condition named non-alcoholic fatty liver disease (NAFLD), resulting from excessive storage of fats in liver cells that are now common among the masses. An […]