Husna, Amity University Kolkata
The data on COVID-19 infections during pregnancy is limited. Although mortality or casualty due to the infection isn’t reported yet some adverse outcomes have been reported in the infants of women with covid-19 infections. The infant born to a COVID-19 infected mother has low birth weight, feeding intolerance, respiratory problems. Other adverse outcomes such as preterm labor and delivery, premature rupture of membranes, intrauterine growth restriction, asphyxia, pneumonia, and stillbirth have also been reported.
Recently, for the first time, COVID-19 infection was diagnosed in a 7 weeks pregnant woman along with liver cytolysis probably due to frequent usage of drugs for treating her repeated implantation failure (RIF). As the symptoms weren’t so severe it was decided to monitor the patient at home according to the guidelines. Eventually, after the treatment, ultrasound scans performed on the 11th week of amenorrhea were returned to normal, the fetus had followed a normal growth with a size of 51 mm and there was no malformation of organs.
According to the guidelines for SARS-CoV-2 infected pregnant women, the patients should be monitored twice a month by ultrasounds for morphological analysis of the fetus. Hepatic assessment should also be done twice a month as the patients with COVID-19 can have a liver injury as found in the blood tests during disease progression. The reason behind liver injury might be a direct viral infection or because of drug hepatotoxicity which happens by chronic usage of some drugs resulting in liver damage.
In conclusion, there has been no injury or harmful impact on the fetus so far. Thus, such findings can contribute to a better understanding of the overall impact of SARS-CoV-2 on pregnancy and childbirth which will help to establish guidelines for the management of laboratory-confirmed SARS-CoV-2 pregnant women.
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SOURCE: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-020-05551-0
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