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  • COVID UPDATE: COVID elixir by Oxford is unsafe? Trials put on hold yet again!

Calcium channels prohibit pathogen entry

Molecules for Life- Thioredoxin System

COVID UPDATE: COVID elixir by Oxford is unsafe? Trials put on hold yet again!
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COVID UPDATE: COVID elixir by Oxford is unsafe? Trials put on hold yet again!

bioxone September 9, 2020September 9, 2020

-Binayak Das, Team bioXone

The highly-awaited trials for the Covid-19 vaccine formulation by Oxford have yet again been put on hold for a second time this year. The reason behind this has to do with certain safety concerns, as informed to Stat News, on Tuesday. This measure was taken by AstraZeneca Plc. right after they observed potentially hazardous reaction-response, in a trial participant. A statement coming directly from AstraZeneca Plc personnel stated that their standard review process instigated a pause to vaccination, so as to allow the review of their safety data. 
The details about what the safety issue is exactly have not yet been made public by neither AstraZeneca nor by the researchers at the University of Oxford, although they mentioned that the patient is not in critical condition and will supposedly, recover soon, according to Stat News.

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Molecules for Life- Thioredoxin System

bioxone September 9, 2020

–Esha Sircar & Dr. Rajib Sengupta, Amity Institute of Biotechnology, Amity University Kolkata The thioredoxin (Trx) system is a major antioxidant system that maintains the intracellular redox state. It contains Trx, a redox-active protein, which regulates the activity of various enzymes including those that function to counteract oxidative stress within the cell. Trx, NADPH, and […]

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Nanopores – As Single-Molecule Sensors

bioxone November 15, 2020November 15, 2020

Surupa Chakraborty, Amity University Kolkata The past decade saw an explosion in the use of nanopore-based technology for DNA/RNA sequencing where Nanopores can be ideally used as single-molecule sensors. Oxford Nanopore Technologies has developed sequencing technologies – the ION series; a miniature nanopore DNA sequencer called the MinION that allows portable and convenient sequencing of high throughput […]

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Hypsibius exemplaris: a tardigrade as an emerging model for mitochondrial enzyme analysis

bioxone December 16, 2020December 16, 2020

Ayooshi Mitra, Amity University, Kolkata Mitochondrial alternative oxidase (AOX) is an enzyme that forms an integral part of the electron transport chain (ETS) in mitochondria. This enzyme is present in the mitochondria of many invertebrates. The expression of AOX in human mitochondria is regarded as a potential therapeutic strategy, regardless of the reason for the […]

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Blocking autophagy to prevent old age organ decline? Find out

bioxone October 1, 2020October 1, 2020

Subhangi Das, Bankura Sammilani College According to a new study published in Nature Cell Biology, to stop the cannibalistic behaviour of an enzyme that can be the key to new drugs that fight against the age-related diseases. Researchers for the first time found out a process showing how the self-eating cellular method which is known […]

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