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May 17, 2025
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Tag: therapeutic

  • BiotechToday
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Cytokine GDF15 regulates a new energy metabolism pathway

BioTech Today October 20, 2021October 20, 2021

Arya Sukumar, College of Agriculture, Vellayani A novel pathway related to the activation of receptors associated with cardiovascular disorders like diabetes, obesity, and hypertension is described in research published in the journal Cell Reports. Many of the antidiabetic effects of PPAR β/δ receptor activators are controlled by cytokine GDF15. The research aids in the discovery […]

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CGRP: A special peptide and its role in Migraine Attacks

BioTech Today August 4, 2021August 4, 2021 1

Sayak Banerjee, Amity University Kolkata Migraine and its chronification: Migraine is a significant primary headache disorder as it ranks the sixth most prevailing disease and the second cause of disability worldwide. This widespread neurological disease is distinguished by headaches which might take place with or without aura. An aura is a kind of sensory disturbance […]

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  • BiotechToday
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A novel CNS-permeable reactivator counters nerve agent exposure

bioxone August 2, 2021August 1, 2021

Sayak Banerjee, Amity University Kolkata Nerve agents, also known as nerve gases, belong to a class of organic chemicals that interrupts the nerves from transferring messages to organs. This interruption takes place due to the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of the neurotransmitter, acetylcholine. So basically nerve agents are AChE […]

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Exosomes’ role in lung cancer metastasis

BioTech Today July 21, 2021July 20, 2021 2

Soumya Shraddhya Paul, Amity University, Noida Lung cancer is one of the leading causes of cancer-associated deaths in the world. According to WHO, around 1.8 million people all around the world succumbed to lung cancer. With the initial onset of tumor progression, metastasis is the cause of 70% of the mortalities. Due to this reason, […]

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“Death Star” in cancer biology- the mutated form of RAS protein

BioTech Today July 3, 2021July 2, 2021

Sayak Banerjee, Amity University Kolkata The scientists at the University of Leeds have discovered a new method of targeting a mutated protein, which is the reason behind most of the fatal cancers. The mutated form of RAS protein is often considered the “Death Star” since it has the potential to resist various treatments. Although RAS […]

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  • BiotechToday
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A new therapeutic avenue in Clostridioides difficile Infection

bioxone June 22, 2021June 21, 2021

Akshita Kumar Clostridioides difficile is an anaerobic Gram-positive bacteria that is capable of forming spores. Clostridioides difficile infection (CDI) is the most common reason behind hospital-acquired gastrointestinal infections and mortality in industrialised nations, with an estimated 223,900 infections, 12,800 deaths, and a $1 billion healthcare cost in 2017. In recent years, there has also been a rise in the number of community-associated […]

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Drug development from traditional to recent methods

bioxone June 7, 2021June 7, 2021 2

Varuni Ankolekar, Clinical Data Manager Traditionally, the discovery of drugs was done by recognizing the active ingredients from traditional remedies or unexpectedly.  Later, Scientists discovered that the interaction of specific chemicals in the drug with biological molecules of the human body serves the purpose of the drug. Later, Chemical pharmacological approaches were made to identify […]

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C28 : Controls the side effects of drugs on the Heart

bioxone May 23, 2021May 22, 2021 1

Aakancha Shaw, St. Xavier’s College, Kolkata There are many such drugs Or rather commonly used drugs that include various types of antibiotics, antinausea and anticancer medications, that have a potential side effect of lengthening Or increasing the electrical event that leads to systole(contraction), thus creating an irregular heartbeat which is known as cardiac arrhythmia called […]

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A new therapeutic target for stomach cancer discovered

bioxone December 17, 2020December 16, 2020 2

Husna, Amity University Kolkata More than one million people around the world are diagnosed with stomach cancer every year. Stomach cancer is an abnormal growth of the cells that tends to develop slowly over many years. Before true cancer develops, the early changes rarely cause any symptoms and therefore go undetected. In its advanced stage, […]

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Identifying Host Factors to Inhibit Entry of SARS-Cov-2 And Ebola Virus

bioxone October 14, 2020October 14, 2020

Sampriti Roy, Asutosh College (University of Calcutta) When speaking of cell mechanisms, there are still a large number of the same that remain largely unknown. From understanding viral pathogenesis to antiviral therapeutics development – the identification of viral mechanisms and understanding how the virus defends itself is crucial. This is the case particularly for those […]

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Breaking News

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AI Literacy in Early Childhood Education: Challenges and Opportunities

Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

Exogenous Klotho as a Cognition Booster in Aging Primates

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