Protein binding to “hidden” DNA- An intriguing concept!
Sneha Singhal, Jaypee Institute of information technology, Noida DNA is present in the form of chromatin fibers tightly wrapped around histones in the cell nucleus. Therefore, rendering the large fraction of DNA surface inaccessible for protein binding. For this problem, several studies began to uncover the various strategies used by DNA-binding proteins. Scientists proposed that […]