High-Grade Serous Ovarian Carcinoma & its radical treatment
Srabani Roy Chowdhury (MAKAUT, WB) HGSC or High-Grade Serous Ovarian Carcinoma is considered to be an aggressive type of ovarian cancer. Deleterious mutations present in the DNA repair gene RAD51C are drivers of defective homologous recombination in High-Grade Serous Ovarian Carcinoma (HGSC). These are emerging biomarkers of PARP inhibitor sensitivity. A PARP inhibitor is targeted […]