Ananya Ghosal, MAKAUT(WB) Protein Trafficking The transportation of proteins to the extracellular space or subcellular compartments is called protein trafficking. Protein quality control contains everything from monitoring protein folding, cellular mechanisms, to detecting abnormal forms. Firstly, proteins are synthesized at cytoplasmic ribosomes, and their destinations are determined by transport signals. Cytosolic proteins are those where […]
Camelia Bhattacharyya, Amity University Kolkata Protein folding and misfolding is widely studied about different diseases and symptoms due to their ability to trigger a stress response in our body, leading to several diseases, even neurodegeneration. When speaking of stress, the endoplasmic reticulum (ER) stress is something on which maximum focus should be given since ER […]
Biswadeep Sen, Amity University Kolkata Recent studies show that Inflammation and Carcinogenic processes are interconnected. Not just because both induce DNA instability, but both are driven by the same pathways (like NF-kB, STAT3, mTOR and MAPKs). The pro-inflammatory cytokines like IL-6, IL-1β, TNF-α and IL-10 mould our immune responses and they are controlled by the […]
