Parnad Basu, Amity University Kolkata What is Parkinson’s disease? Parkinson’s disease is a neurodegenerative disorder that affects neurons (dopamine-producing) of substantia nigra. Symptoms of this disease develop slowly over the years and vary from person to person. The cause of Parkinson’s disease is not well known which makes it difficult to cure. However, medications and […]
Camelia Bhattacharyya, Amity University Kolkata Protein folding and misfolding is widely studied about different diseases and symptoms due to their ability to trigger a stress response in our body, leading to several diseases, even neurodegeneration. When speaking of stress, the endoplasmic reticulum (ER) stress is something on which maximum focus should be given since ER […]
Surupa Chakraborty, Amity University Kolkata Scientists cured lost eyesight in mice by genetically reprogramming the neurons that make up the optic nerve. They used the mice eye as a model tissue to show that the ectopic expression of genes like Oct4, Sox2, and Klf4 (OSK) in mouse retinal ganglion cells can help in restoring vision […]
Avipsha Datta, Rajabazar Science College, University of Calcutta The Bcl-2 family of proteins are the prime players in the mitochondrial pathway of apoptosis. Malfunctioning of 1 or more members can lead to cancers, neurodegenerative diseases and various other developmental disorders. The pro-apoptotic member BAX plays a central role in apoptosis with the assistance of mitochondrial […]
