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June 4, 2025
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Tag: Mutation

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Genetic pathway behind neurological disorder in Rett syndrome

BioTech Today July 9, 2021July 8, 2021

Sneha Singhal, Jaypee Institute of information technology, Noida What is the Rett Syndrome? Rett syndrome also called RTT, is a rarely occurring genetic neurological or brain disorder. As a developmental disorder, it is found mostly in girls. There are severe functional impairments associated with Rett syndrome, affecting nearly every aspect of the child’s life. Language […]

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PhyliCS: A Python library package to quantify Intra-tumor Heterogeneity

BioTech Today July 5, 2021July 4, 2021

Sayak Banerjee, Amity University Kolkata Intra-tumor Heterogeneity ( ITH) Aggregation of a distinct set of somatic mutations leads to the generation of tumors. The set of mutations assembled by the prime tumor is known as clonal and the mutations which take place in pre-existing tumors comprise cancer cell sub-populations is known as subclonal. Consequently, the […]

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Comeback of tuberculosis- but its drug-resistant now!

BioTech Today July 3, 2021July 2, 2021 1

Vaishnavi Kardale, Bioinformatics Centre, Savitribai Phule Pune University Tuberculosis is a major health concern in many low and middle-income countries. TB continues to be the top killer infectious disease in the world. In 2019 over 10.0 million people were affected with TB and 1.41 million deaths were attributed to it. TB affects all countries of […]

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“Death Star” in cancer biology- the mutated form of RAS protein

BioTech Today July 3, 2021July 2, 2021

Sayak Banerjee, Amity University Kolkata The scientists at the University of Leeds have discovered a new method of targeting a mutated protein, which is the reason behind most of the fatal cancers. The mutated form of RAS protein is often considered the “Death Star” since it has the potential to resist various treatments. Although RAS […]

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G-quadruplexes as functional elements of the human genome

BioTech Today July 2, 2021July 1, 2021

Avani Dave, Jai Hind College Natural selection has evidently preserved several specific sites in the human genome that allow an atypical 3-D conformation of the DNA which are referred to as G-quadruplexes (G4s). A new study demonstrates an increased occurrence and high stability of these not-so-usual G-quadruplexes if they are situated either in the sequences […]

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SETD2 in histone and tubulin methylation

bioxone June 21, 2021June 21, 2021 2

Saakshi Bangera, DY Patil School of Biotechnology and Bioinformatics Microtubules are the constituents of the cytoskeleton that help maintain the shape and structure of a cell as well as mediate intracellular transportation. They essentially are polymers of tubulin units and require post-translational modifications (PTMs) to function correctly. They undergo several modifications like methylation, acetylation and […]

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PARP inhibitors: One class of drugs for Multiple Forms of Cancer

bioxone June 10, 2021June 10, 2021 3

Sayak Banerjee, Amity University Kolkata Scientists have come over a class of drugs utilized in the treatment of breast and ovarian cancer which might be effective in other types of diseases with inadequate treatment alternatives. These are called PARP inhibitors which have the potential to kill cancer cells carrying a defect in the Polybromo 1(PBRM1) […]

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Facts on how the brain matures.

bioxone June 2, 2021June 2, 2021 1

Saptaparna Pal, Amity University Kolkata Some researchers from The Virginia School of Medicine have shed new light on how our brains mature; disclosing that the very last step in cell proliferation is important for the brain to reach its actual size and function. The new findings that are published in The Journal of Neuroscience identify […]

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A hybrid strain of Indian and UK variant identified in Vietnam

bioxone May 31, 2021May 31, 2021

Prama Ghosh, Amity University Kolkata A new variant of Coronavirus has been detected in Vietnam which is a combination of the Indian and UK variants according to the health minister on Saturday. This new hybrid strain spreads quickly by air and is more dangerous.  After examining the genetic makeup of the virus that recently infected […]

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Diabetic patients and Covid-19 pandemic

bioxone May 22, 2021May 22, 2021 1

Husna, Amity University Kolkata COVID-19 is a highly contagious viral infection that can mainly affect the respiratory system. It is caused by the SARS-CoV-2 virus which has the ability to mutate. Due to frequent mutations, the COVID-19 strains are highly virulent and tend to infect more rapidly, leading to a rapidly evolving pandemic. The impact […]

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Breaking News

The Corrosion Prediction from the Corrosion Product Performance

Nitrogen Resilience in Waterlogged Soybean plants

Cell Senescence in Type II Diabetes: Therapeutic Potential

Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP

AI Literacy in Early Childhood Education: Challenges and Opportunities

Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

Exogenous Klotho as a Cognition Booster in Aging Primates

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