Richa Prakash, MSc, Central University of Punjab DNA or Deoxyribonucleic Acid is a complex molecular structure containing all the genetic information inside the cells required for the development and functioning of any organism. DNA damage occurs every day by the byproducts formed during cellular metabolism and ionizing radiations. DNA damage is any change in the […]
Moumita Ghosh, Amity University Kolkata Introduction Hutchinson-Gilford progeria syndrome (HGPS) is a rare disease that affects 1 in every 4-8 million infants worldwide. It is a disease characterized by accelerated aging in humans. Progeroid syndromes (PSs) can be identified as rare and fatal genetic disorders characterized by various features and symptoms of premature physiological aging. […]
Sayak Banerjee, Amity University Kolkata Adaptive laboratory evolution has become a substantial tool for the development of microbial strains with enhanced genetically modified features. The long-term Escherichia coli evolution experiment is a good example. It has emphasized how evolution under adequate conditions can be utilized to understand adaptive processes. These experiments have helped to determine the possible evolutionary […]
Srabani Roy Chowdhury (MAKAUT, WB) Despite all the global malaria control measures, more than a 200million malaria cases are seen, out of which 0.5million people have succumbed to death. The attempts for new drugs have led to the identification of various chemical compounds that can destroy the parasites in the different stages of their life […]
Priasha Dutta, Amity University Kolkata WHERE IT ALL BEGAN We have probably heard of “dark matter”, which is believed to make up more than a quarter of the universe. Although its presence is confirmed, scientists have not been able to detect it yet. Recently, elusive genetic matter has been detected in the genome. This biological […]
Varuni Ankolekar, Quartesian When you want to eat or prepare super delicious appetizers, one of the vegetables that come to mind is Cauliflower, which is also used to make many more dishes. Ever wondered about stunning beautiful patterns observed on Cauliflowers and found yourself lost while staring at this vegetable? If yes, the new research […]
Saptaparna Dasgupta, Bennett University SARS-CoV-2, a strain from the Coronavirus family, is responsible for the ongoing global pandemic of COVID-19, taking the lives of millions of people via an infectious respiratory illness. Several studies have been conducted on this virus to find target proteins responsible for the infection as a therapeutic. Thus, spike (S) protein […]
Saptaparna Dasgupta, Bennett University Human exonuclease V (EXO5) is an ATR-regulated nuclease that is specific to the DNA structure. It is also associated with BLM, to mark the start point of the replication fork in a strand of DNA. Research states that an elevated level of EXO5 in tumor cells results in increased mutation within […]
Agrima Bhatt, Rajasthan University What is HJMD? HJMD or Hypotrichosis with macular dystrophy is an autosomal syndrome commonly found in young children. It is caused by a mutation in a gene CDH3, responsible for encoding a protein in hair follicles, and the retinal pigment epithelium (RPE). CDH3 encodes a glycoprotein known as P-cadherin, found at […]
Agrima Bhatt, Rajasthan University Drugs identifying cancer genes: To understand drug-target interaction, let’s first cover our bases to know what is meant by receptor and a ligand. Receptors are defined as the macromolecules present either on the cell surface or in the cytoplasm which is involved in the cell interaction through signalling. Molecules like drugs, […]
