Shrestha Sherry Chakraborty, Amity University Kolkata Cancer is marked by the uncontrollable growth of malignant cells which then spread by metastasizing to different regions of the body. To battle against this deadly disease, a variety of treatments have evolved with years of research and development overcoming complex challenges and hurdles. The most well known of […]
Husna, Amity University Kolkata Oncolytic viruses are genetically engineered for the destruction of cancer or tumour-causing cells specifically. They’re delivered for treatment inside the body via intravenous injection. In 2015, one such oncolytic virus was approved by the FDA for treating skin cancer, melanoma. A major obstacle in the application of oncolytic adenoviruses is that […]
Prama Ghosh, Amity University Kolkata Past proof in mice has exhibited that NK cell-inferred IFN-gamma can advance immunoevasion by chiselling the immunogenicity of creating tumours in a process known as cancer immunoediting. This process includes the disposal of the high immunogenic unedited tumour, followed by the inevitable break of less immunogenic altered tumour cell variants […]
Prama Ghosh, Amity University Kolkata Recent studies have shown that tumor invasion and progression are enhanced by the interaction of tumor cells with the surrounding tissues. To study the same, molecular microarray analyses of human Gastric cancer cell lines NUGC-3 co-cultured with platelets for 48 h were performed. Functional analyses of the interaction between NUGC-3 […]
Rohit Bhattacharjee, Amity University, Kolkata Osteosarcoma is a rare malignant bone tumour found in adults and children. It is characterized by early lung metastasis and poor prognosis that seriously the physical and mental health of patients. Chemotherapy and surgery include the main clinical treatment however, recurrence of metastasis remains the poor prognosis. Advances in the […]
Biswadeep Sen, Amity University Kolkata Recent studies show that Inflammation and Carcinogenic processes are interconnected. Not just because both induce DNA instability, but both are driven by the same pathways (like NF-kB, STAT3, mTOR and MAPKs). The pro-inflammatory cytokines like IL-6, IL-1β, TNF-α and IL-10 mould our immune responses and they are controlled by the […]
Chitra Roy, University of Calcutta High-Grade Serous Ovarian Carcinoma (HGSOC) is one of the most common and deadliest types of ovarian cancer. This gynaecological malignancy is a type of tumour which arises from the ovary, fallopian tube, or peritoneum. The tumour microenvironment is very complex and 40% of this tumour mass contains Macrophages. Macrophages originate […]
Saptaparna Pal, Amity University Kolkata Nano sealed motor particles represents a group of efficient molecules that can precisely respond to the biological microenvironment and improves therapeutic results. Hence, a 2D nanosheet based catalytic nanometre with chemotaxis behaviour is designed for enhanced and advanced drug delivery towards the Tumor microenvironment. The 2D structure of nanometre allows […]
Shrestha Sherry Chakraborty, Amity University Kolkata. Cells have employed various ways to travel in the biological system. Somatic cells in our body adhere to cell surfaces for their movement. On the other hand, sperm cells and some bacteria move by the means of flagella. White blood cells are the specialized cells of the immune system. […]
