Charvy Rana, Department of Pathology, AIIMS, New Delhi What is MYCN protein? Cancer often involves the inactivation of tumor-suppressor genes and/or over-activation of oncogenes. The MYCN proto-oncogene is one such example, implicated for its amplified or “oncogenic” status in several neuronal and non-neuronal cancers (those of lung, ovaries, prostate, and more)1. Normally expressed during the […]
Hari Krishnan R, SRM Institute of Science and Technology An Epithelial-Mesenchymal transition is a reversible event that occurs in embryonic development and cancer. As indicated by the name, this process involves the conversion of epithelial cells to mesenchymal cells. Cells undergoing this process are highly capable of migration, proliferation, and differentiation into various cell types. […]
Agrima Bhatt, Rajasthan University Oncological sciences have moved far in terms of research and development, leading to many novel therapies currently in use. Despite research on tumors and their causes, cancer remains the leading cause of death worldwide. The most popular approach to cancer treatment has been chemotherapy and radiation therapy. These approaches are not […]
Soumya Shraddhya Paul, Amity University, Noida Lung cancer is one of the leading causes of cancer-associated deaths in the world. According to WHO, around 1.8 million people all around the world succumbed to lung cancer. With the initial onset of tumor progression, metastasis is the cause of 70% of the mortalities. Due to this reason, […]
Esha Mukherjee, Amity University Noida Colorectal cancer is a cancer that begins in the colon or the rectum. According to a study published in the journal BMC Public Health, insufficient exposure to Ultraviolet-B (UVB) light from the sun may be associated with an increased risk of colorectal cancer, particularly in older age groups. Vitamin D […]
Saptaparna Dasgupta, Bennett University The intermediate and transitory reaction of breast-tumour stiffness to pathological rigidity has been carefully investigated in their native microwave environment. However, it remains unclear how the main phenotypes of stiffness caused by the cancer cell are stained in vivo over a while. Certain mechanisms are associated based on how fibrotic-like matrix […]
Koustav Maiti, Ramakrishna Mission Vivekananda Centenary College, Rahara Cancer can be defined by two properties: 1. They reproduce cells by the violation of normal cell growth and division, and 2. They occupy other regions conserved for other normal cells by the properties of invasion and metastasis. Metastasis is the most important character of cancer cells […]
Anannya Roy, Amity University Kolkata What did Oscar Wilde mean when he said-“Life imitates art more than art imitates life”? We as biologists concern ourselves with the Science of life and indeed it is not uncommon that, quite often the art of discovery derives its inspiration from nature itself. Synthetic Biology is a modern interdisciplinary […]
Koustav Maiti, Ramakrishna Mission Vivekananda Centenary College, Rahara A normal cell always has the characteristics of regulated cell division, proliferation and lastly undergoes apoptosis (programmed cell death). But when the cell does not have control over its division, it causes a tumor. When the neoplastic cells are clustered together but don’t spread anywhere else within […]
PRAGYA SANTRA, AMITY UNIVERSITY KOLKATA The history of cancer research has always been a mystery in the result. Recently it was reported that cancer cells adapted themselves to grow and proliferate in an inflammatory environment. ENPP1, a readily accessible molecule found on the surface of cancer cells plays a major role in this mechanism. Naturally, […]
