Husna, Amity University Kolkata What is a BRAF inhibitor and what is its role? BRAF is a gene that is present on chromosome 7q34. It encodes a protein that has the ability to regulate the MAP kinase/ERKs-signaling pathway. These pathways have a crucial role in regulating cell division, differentiation, and the growth and proliferation of […]
Madhavi Bhatia, NIPER Guwahati. The gut flora of humans acts as a major factor that influences the health of an individual. The microbiome may affect the disease progression and response to immunotherapy. So, the gut microbiome can act as a cancer biomarker. For analyzing this high throughput 16S-rRNA-gene-based approach is utilized to detect a genuine […]
Husna, Amity University Kolkata Oncolytic viruses are genetically engineered for the destruction of cancer or tumour-causing cells specifically. They’re delivered for treatment inside the body via intravenous injection. In 2015, one such oncolytic virus was approved by the FDA for treating skin cancer, melanoma. A major obstacle in the application of oncolytic adenoviruses is that […]
Sayantani Halder,Amity University Kolkata Xeroderma Pigmentosum (XP) is a rare inherited human syndrome (recessive autosomal trait), caused due to the defect in mechanism of repairing of damaged DNA (or mutated DNA) characterized by hypersensitivity to sunlight, developing skin cancer at a very early age. The primary cause of this disease is the absence of a […]
Rohit Bhattacharjee, Amity University Kolkata Skin cancer, the most common kind of cancer, is mainly caused due to excessive exposure to the UV rays from the sun. They are of two types:- melanoma ( develops from pigment-producing skin cells called melanocytes) and non-melanoma (developed from other skin cells). Though non-melanoma skin cancer is more widespread, […]
