Priyanka Saha, Amity University Kolkata Introduction Senolytics are a special class of drugs that eliminate old or senescent cells (SC) in the body. They are developed to prevent or delay age-related diseases in humans. The word senolytics is connected to “Senostatic” which refers to suppressing senescence. Most of the senolytic agents are in the early […]
Avani Dave, Jai Hind College Inborn errors of immunity (IEI) are a group of approximately 400 monogenic diseases characterized by recurring, severe, or uncommon infections, as well as autoimmunity and autoinflammation. The synthesis of the clinical phenotype, the findings of immunological testing, and the results of genetic testing have identified the main pathogenic mutations required […]
Avani Dave, Jai Hind College Excessive inflammation and disruption of the alveolar-capillary barrier result in lung edema and decreased gas exchange in acute lung injury (ALI), a frequent consequence of sepsis. ALI continues to be a major cause of morbidity and death in critically sick patients, emphasizing the need for new treatment approaches. Due to […]
Aayushi Gaur, U. I. E. T., Kurukshetra University Doctors battled to keep patients breathing in the early months of the COVID-19 pandemic, focusing mostly on treating lung and circulatory system damage. However, evidence of neurological consequences was already collecting at the time. Some COVID-19 patients were suffering from delirium, which manifested as confusion, disorientation, and […]
Shayan Ahmed, Jamia Millia Islamia, New Delhi Pediatric Severe Malaria: Malaria continues to be a major source of illness and mortality in children, with an estimated 272,000 deaths in children under the age of five worldwide in 2018. Cerebral Malaria (CM) and Severe Malarial Anaemia (SMA) are two frequent symptoms of pediatric Severe Malaria (SM) in […]
Saptaparna Dasgupta, Bennett University Inflammation is a common condition that occurs with swelling and stiffness of the joints. It is the responsive mechanism of how the body responds in order to protect itself from injury, infection, or any illness. Thus, a certain amount of inflammation stands to be necessary for the proper functioning of the […]
Sayak Banerjee, Amity University Kolkata Migraine and its chronification: Migraine is a significant primary headache disorder as it ranks the sixth most prevailing disease and the second cause of disability worldwide. This widespread neurological disease is distinguished by headaches which might take place with or without aura. An aura is a kind of sensory disturbance […]
Sayak Banerjee, Amity University Kolkata Autoimmune Hepatitis and Autoimmune sclerosing cholangitis Autoimmune hepatitis (AIH) is a complex disease that occurs in patients of all ages present in both acute and chronic forms. Having no disease-specific test, it is a diagnosis of exclusion with one-third of patients suffering from advanced liver disease. Autoimmune sclerosing cholangitis (ASC) […]
Avani Dave, Jai Hind College The good cholesterol has stood up to the prefix given to it as researchers claim it’s added advantages. In addition to the existing features of good cholesterol, it is now known to be associated with improved liver health. HDL is traditionally known for absorbing cholesterol and delivering it to the […]
Sayak Banerjee, Amity University Kolkata Human Epithelial Tissue Integrity Human epithelia are tissues that are seen in various parts of the body in the form of internal mucosa, epidermis, etc. They are made up of several layers of neighbouring cells and they act not only as a physical barrier but also as a chemical barrier. […]
