Sayak Banerjee, Amity University Kolkata Nerve agents, also known as nerve gases, belong to a class of organic chemicals that interrupts the nerves from transferring messages to organs. This interruption takes place due to the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of the neurotransmitter, acetylcholine. So basically nerve agents are AChE […]
Priyanka Saha, Amity University Kolkata Introduction: The rarest form of blood type on Earth is ‘Rh-null blood’, also known as ‘Golden blood’. The rationale behind being rare is due to the lack of all the Rh (rhesus) antigens (proteins) on the surface of red blood cells (RBC). RBC of these people has an unusual shape, […]
SUMEDHA GUHA, TECHNO INDIA UNIVERSITY Reelin is an extracellular glycoprotein that acts as a key regulator for different steps in brain wiring and neuronal cell migration. Reelin signalling is required for axonal targeting, regulation of dendritogenesis, and spine formation in mature neurons. It also plays an important role in ensuring hippocampal integrity, synaptic plasticity, and […]
Sayan Roy, Pondicherry University mRNA-1273 is a messenger RNA (mRNA) vaccine, designed to fight against Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2). It is developed by a US-based pharmaceutical company- Moderna, in association with NIAID Vaccine Research Center. The mRNA-1273 vaccine encodes for the SARS-CoV-2 full-length spike glycoprotein trimer ‘S-2P’, but modified to incorporate two proline substitutions […]
Prama Ghosh, Amity University Kolkata The alarming hypothesis that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic to be around for several years calls for rapid and successful therapies. Though anti-SARS-CoV-2 spike monoclonal antibodies originated from mice have shown robust performance in various immunoassays including western blotting, ELISA, immunofluorescence, and immunoprecipitation, there is still a […]
