Debarati Basu, Makaut (WB) Cancer is distinguished by heterogeneous morphological, phenotypic, and genomic profiles. For patients to undergo proper treatment identification of cancer subtypes plays an important role. Meta-data is being produced in the fields of genomics, epigenomics, and transcriptomics which will help to identify underlying root causes of cancer on a gene level. It […]
Shayan Ahmed, Jamia Millia Islamia, New Delhi Biosynthetic Gene Clusters in Streptomyces: Streptomyces genomes have a huge reservoir of uncharacterized Biosynthetic Gene Clusters (BGCs) producing drug-like compounds, sparking renewed interest in these species. However, in laboratory circumstances, a substantial percentage of these BGCs fail to generate measurable amounts of the anticipated chemicals. As a result, […]
Supriyo Mukherjee, Kalyani Mahavidyalaya Scientific researches have unveiled a novel conformation of gigantic, extrachromosomal DNA in mud-dwelling archaea, as stated in a preprint posted on July 10, 2021, on bioRxiv. Extrachromosomal elements (ECE) comprise structures such as plasmids, megaplasmids, viruses, etc. which give rise to attributes like antibiotic resistance in bacteria. However, as reported in […]
Saakshi Bangera, DY Patil School of Biotechnology and Bioinformatics Copy number variation is the phenomenon of deviation of an individual from a diploid state of its genome. Normally, humans have two copies of each locus in their genome. Any deviation from this can cause Mendelian disorders. Due to the availability of short-read sequencing technologies, several […]
Nandini Pharasi, Jaypee Institute of Information Technology Oral cancer, also known as mouth cancer develops in any part of the mouth due to genetic mutations. The reasons for this could be the usage of tobacco, heavy liquor, or human papillomavirus (HPV) infection. Symptoms include a lump or a red or white patch inside the mouth […]
Shivani Vaja, former student President Science College DNA Sequencing is the systematic process of determining, performing, and analyzing the sequence of nucleotides ( the order of adenine, guanine, cytosine, and thymine nucleotides ) in DNA. The technique of resolving DNA sequence was known as Sanger sequencing. This methodology included the separation of fluorescently labeled DNA […]
Soumya Shraddhya Paul, Amity University Noida For a very long time, monoclonal antibodies have been used in various fields (cancer studies) but currently, they are being used to counteract the effects of SARS-CoV-2 and its variant by being an active compound in the vaccine as well as therapeutic drugs. Hence, to understand B cell genomics […]
Sumedha B S, Bangalore University Long-read sequencing (LRS), also called third-generation sequencing, offers a number of advantages over short-read sequencing such as Illumina’s NovaSeq, NextSeq, HiSeq and MiSeq instruments. Long-read sequencing technologies could permit the assembly of genomes, which is capable of revolutionizing genomics. It has the potential to reveal the full spectrum of human […]
Aqsa, Jamia Millia Islamia A nucleosome is a DNA segment of 147-bp coiled around a histone octamer. Each histone octamer is made up of two copies of each of the histone proteins H2A, H2B, H3, and H4. It is the fundamental subunit of chromatin. Although it seems that the nucleosome has its significance only in […]
Aakancha Shaw, St. Xavier’s College, Kolkata Researchers, for the first time, have been successfully able to sequence the entire genome from the skull of PeşteraMuierii 1. She is a woman who lived about 35,000 years ago in today’s Romania. Muierii woman is somehow related to Europeans, though she is not a direct ancestor. This study […]
