Sneha Singhal, Jaypee Institute of information technology, Noida Oxford University researchers have announced that volunteers have received the first HIV (Human immunodeficiency) vaccination to find an effective cure for the virus. It has been 40 years since an effective HIV vaccine has been discovered. Trials are underway to develop an effective vaccine against HIV. The […]
Richismita Hazra, Amity University Kolkata Single-cell signaling responses are now measurable, but their interpretation is still restricted. Interpretation of dose-response based on single-cell data is also not accurately predictable. Here, probabilistic modeling and information-theory have been used to inaugurate fractional response analysis (FRA). This technique quantifies changes in the fraction of cells with provided response […]
Prama Ghosh, Amity University Kolkata Severity and death from Coronavirus disease 2019 (Covid-19) are associated with the older population; testing such vaccine candidates is important to prevent infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A phase 1, open-label trial with an escalated dose of messenger RNA vaccine, mRNA-1273, which encodes the stabilized prefusion […]
RUCHITA KARMAKAR, AMITY UNIVERSITY KOLKATA BET (Bromodomain and extra terminal domain) proteins are described to be epigenetic and anti-cancer drug targets. This was the first-in-human study that judged the pharmacokinetics and prior activity of ODM-20, the inhibitor of BET in patients having solid tumours. The main objective was to determine the tolerability, dose-limiting toxicities (DLT), […]
