Inducing DNA-protein crosslinks and 5-azacytidine to study genetic mutation in Escherichia coli
Souradip Mallick, National Institute of Technology, Rourkela DNA–protein crosslinks induce SOS response as it is mutagenic and 5-azacytidine induces bacterial damage and stimulate homologous recombination. All these consequences of DNA–protein crosslinks and 5-azacytidine were investigated on E.coli DNA–protein crosslinks (DPCs) are mainly formed when a nucleotide residue on DNA forms a covalent bond with a […]