Anish Pyne, Indian Institute of Technology Kharagpur With the growing prowess of personalized medicines and molecular drugs, a group of methods took the central stage allowing the introduction of highly specific changes within the genome by either adding or deleting, or substituting any desired sequence, thus modifying the natural characteristics of a gene. And this […]
Jayateerth S Bhavikatti, CSIR-National Chemical Laboratory, Pune. We have recently come across that the Nobel Prize for Chemistry 2020 is awarded to Emmanuelle Charpentier and Jennifer A. Doudna for developing CRISPR/Cas9 genetic scissors. This process requires guide RNA for cutting DNA at specific locations in the genome. Many techniques in molecular biology require template nucleotide […]
Sashreek Ganguli, Amity University Kolkata Sickle cell disease (SCD) is a set of blood disorders inherited from parents. It is a genetic disorder caused due to A-to-T base mutation within codon 6 of the HBB/Beta-globin gene (which is a part of haemoglobin A/ HgbA) responsible for the glutamic acid to valine substitution. It affects the […]
