S U Vandhana, School of Biosciences and Technology, VIT-Vellore Introduction Cystic fibrosis (CF) is a notable example of a chronic disease whose manifestations are visible as dysfunctional, hyperinflammatory immune response with chronic pulmonary infections creating a huge catastrophe to the airways. This leads to substantial morbidity accompanied by shortened life span. Being an opportunistic pathogen, Pseudomonas […]
Shenade Annie Kerketta, Amity University Kolkata Medical devices (MD) such as Venous catheter (CVC), abdominal drain tube, and Foley’s catheter tip are used in patients to transfer fluids. These devices tend to harbour certain microbial strains that produce biofilm. Biofilm is a polymeric matrix that conceals several bacterial strains into a single unit and provides antibiotic resistance. The […]
Supriyo Mukherjee, Kalyani Mahavidyalaya Scientific researches have unveiled a novel conformation of gigantic, extrachromosomal DNA in mud-dwelling archaea, as stated in a preprint posted on July 10, 2021, on bioRxiv. Extrachromosomal elements (ECE) comprise structures such as plasmids, megaplasmids, viruses, etc. which give rise to attributes like antibiotic resistance in bacteria. However, as reported in […]
Husna, Amity University Kolkata What is Antibiotic resistance (AR)? Antibiotic resistance (AR) is the biological phenomenon that occurs when germs like bacteria become resistant to an antibiotic and develop an ability to defeat the drugs that are designed to kill the bacteria. That means the bacteria continue to grow instead of getting killed by the […]
Richa Prakash, Central University of Punjab Currently, we rely on the enrichment method for the detection and identification of any bacterial infection. This may include enrichment bacterial culture (increasing the number of the organism of interest to a level it can be detected) or PCR (Polymerase Chain Reaction) to amplify the nucleic acids to increase […]
Vaishnavi Kardale, Bioinformatics Centre, Savitribai Phule Pune University Tuberculosis is a major health concern in many low and middle-income countries. TB continues to be the top killer infectious disease in the world. In 2019 over 10.0 million people were affected with TB and 1.41 million deaths were attributed to it. TB affects all countries of […]
Vaishnavi Kardale, Bioinformatics Centre, Savitribai Phule Pune University Oral health is fundamental to the health and wellbeing of an individual. Dental caries is a pathological process that causes tissue destruction. This disease affects quite a huge population across the globe. If left untreated caries can increase plaque retention and lead to severe periodontitis. Periodontitis causes […]
Shayan Ahmed, Jamia Millia Islamia, New Delhi Antibiotic resistance happens to be an important phenomenon emerging as a defence mechanism in bacteria. Antibiotic resistance mechanisms are the reason bacteria are able to counter the effects of antibiotics. Immeasurable and indiscriminate use of antibiotics ever since their discovery has contributed to the development of antibiotic resistance. […]
Sristi Raj Rai, Amity University Kolkata Handicapped microbes that survive drug attacks are more dangerous than the living ones, as very soon they develop resistance to that specific drug. Macrolides, a class of broad-spectrum antibiotics that has a macrocyclic structure are produced by strains of Streptomyces. These are generally prescribed in case of bacterial infections […]
Devyani Goswami, Amity University Kolkata Another threat to human civilization apart from the current COVID-19 situation is the growing risk of antibiotic-resistant bacteria due to overuse and un-prescribed consumption of antibiotics. An annual death of more than 2 million all across the globe made researchers find out a solution on how to control this risk. […]
