Skip to content
Tagged COVID-19 Biotechnology SARS-CoV-2 Life Science cancer CORONAVIRUS pandemic
BioXone

BioXone

rethinking future

June 6, 2025
  • About
  • BiotechTodayNews
    • IndiaWeekly Biotech News of India
    • WorldWeekly Biotech News of The World
  • DNA-TalesArticles
    • BiotechnopediaInteresting articles written by BioXone members and associates.
    • Scientists’ CornerArticles from the pioneers of Biotechnology.
    • Cellular CommunicationInterview of greatest researchers’ in the field.
  • Myth-LysisFact Check
  • Signalling PathwayCareer related updates
    • ExaminationsExamination related articles.
    • Job and InternshipJobs and Internship related articles.
  • Courses
  • Contact

Most Viewed This Week

October 17, 2023October 16, 2023

The Corrosion Prediction from the Corrosion Product Performance

1
October 1, 2023September 30, 2023

Nitrogen Resilience in Waterlogged Soybean plants

2
September 28, 2023September 28, 2023

Cell Senescence in Type II Diabetes: Therapeutic Potential

3
September 26, 2023September 25, 2023

Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP

4
September 25, 2023September 25, 2023

AI Literacy in Early Childhood Education: Challenges and Opportunities

5
September 22, 2023October 1, 2023

Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

6

Search Field

Subscribe Now

  • Home
  • BiotechToday
  • A systematic framework in quantifying the cause of a disease

Cholesterol used to recognize substrate by γ-Secretase

Romanesco cauliflower & its spiraling fractal shape

A systematic framework in quantifying the cause of a disease
  • BiotechToday
  • World

A systematic framework in quantifying the cause of a disease

bioxone July 28, 2021July 27, 2021

Mustafa Vora, DY Patil University, Navi Mumbai

Emerging market economies, low and middle-income countries face parallel challenges of high premature mortality due to communicable as well as non-communicable diseases (CDs and NCDs). On the other hand, developing countries face severe resource constraints. It is important to understand the evolution of these diseases in the short to medium term and the involvement of tradeoffs in decreasing the burden of one disease versus another.

Academic and non-academic institutions have put forward the disease, country-specific mortality, and life expectancy forecasts. The translation of changes in health outcomes into currency is very useful as it allows one to compare the changes in life expectancy against policy or intervention costs. It also allows policymakers to combine such monetary estimates with information on changes in other welfare outcomes, across and beyond health sectors. It helps in calculating the country’s full income which is useful for health policymakers to increase investments in improving social health. Thus the development of an analytical framework took place, this framework quantifies in monetary terms, changes annual age-sex mortality due to various NCD and CDs.

A recent study to develop the analytical framework:

Disease-specific IEMV (income equivalent monetary value) was estimated and its applications were presented using publicly available estimates on mortality rates, population, and income across low, lower-middle, and upper-middle-income countries (LIC, LMIC, UMIC) between the years 2017 to 2030. The LICs had a gross national income per capita lower than $1005. Whereas the LMICs and UMICs fall in the range between $1006 to $3995 and $3995 to $12,235 respectively. Eight disease categories in these countries were classified by the Global Burden of Disease Study. Three steps are involved in the IEMV estimation.

Step 1 was the estimation of changes in mortality risks of high or low-performance routes and base case routes. The age-sex mortality rate for a particular disease in a particular country was determined at a particular time of the year. Three mortality trajectories were determined. Base-case, high performance, and low-performance trajectories. This was followed by estimating the differences in the mortality risks between the three trajectories.

Step 2 was estimating the IEMV of changes in the mortality risk. The monetary value associated with standardized mortality units is called the value of a standardized mortality unit (VSMU). To estimate VSMU for each disease category, the estimation of VSL for each country in each year was done. VSL is the willingness to pay for a small reduction in the risk of mortality. The change in mortality risk between the three trajectories was multiplied by the respective VSMU to calculate the IEMV.

Step 3 was the final step. It was a sensitivity analysis. The reports were summarised by taking an aggregate of the age group year across all countries.

Results and analysis of the study:

Regarding the NCDs, the absolute monetary value associated with changing mortality risk was the highest for cardiovascular diseases in the older age group. A connection was established between changing mortality rate from base case to high-performance trajectory and high monetary value for CDs and also in the younger age group. Two key results emerge from the study. The value of curbing both NCD and CD-specific mortality is very high for low and middle-income countries, although the age groups differ. Countries could experience major hitch if NCD control is not scaled up. This method of estimating the IEMV can be useful for policymakers in providing critical input into estimating the value for money in curbing NCDs and CDs.

Covid-19 is having a devastating effect on individuals affected by NCDs because of which the economic burden of disease framework is important. The framework of this study may help in pointing out the high value for money interventions for optimized disease control.

Also read: Norovirus cases double: England warned by officials

Reference:

  1. Khadka, Aayush, and Stéphane Verguet. “The Economic Value of Changing Mortality Risk in Low- and Middle-Income Countries: A Systematic Breakdown by Cause of Death.” BMC Medicine, vol. 19, no. 1, July 2021, p. 156. BioMed Central, https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-021-02029-x
  2. Mathers, Colin, et al. “Global and Regional Causes of Death: Patterns and Trends, 2000–15.” Disease Control Priorities: Improving Health and Reducing Poverty, edited by Dean T. Jamison et al., 3rd ed., The International Bank for Reconstruction and Development / The World Bank, 2017. PubMed, http://www.ncbi.nlm.nih.gov/books/NBK525280/.

Also read:

  • The Corrosion Prediction from the Corrosion Product Performance
  • Nitrogen Resilience in Waterlogged Soybean plants
  • Cell Senescence in Type II Diabetes: Therapeutic Potential
  • Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP
  • AI Literacy in Early Childhood Education: Challenges and Opportunities

Share this:

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X

Related

Tagged and upper-middle-income countries communicable diseases emerging markets economic framework health sector IEMV low-income lower-middle-income mortality rate mortality risk mortality trajectories non-communicable diseases

2 thoughts on “A systematic framework in quantifying the cause of a disease”

  1. Pingback: High risk of COVID-19 in organ transplant patients - BioXone
  2. Pingback: Transcriptome-wide study of Botrychium lunaria fern - BioXone

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Next Post
  • BiotechToday
  • World

Romanesco cauliflower & its spiraling fractal shape

bioxone July 28, 2021

Varuni Ankolekar, Quartesian When you want to eat or prepare super delicious appetizers, one of the vegetables that come to mind is Cauliflower, which is also used to make many more dishes. Ever wondered about stunning beautiful patterns observed on Cauliflowers and found yourself lost while staring at this vegetable? If yes, the new research […]

Romanesco cauliflower

Related Post

  • BiotechToday
  • World

The Significant Impact of the New Normal on rural communities

bioxone December 21, 2020December 21, 2020

Sampriti Roy, University of Calcutta Along with masks and online meetings, what has been unanimous for all age groups and professions since the beginning of the pandemic or the new normal is ‘struggle.’ The mental and physical struggles in this pandemic have been one of a kind and massive in proportions. But one of the […]

Share this:

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X
  • BiotechToday
  • FEATURED
  • Latest
  • World

COVID UPDATE: Coronavirus was fabricated in government-controlled Wuhan lab, claims Chinese virologist, Dr. Li-Meng Yan

bioxone September 14, 2020September 14, 2020

–Sagnik Nag, Amity University Kolkata The emergence of an exceedingly pathogenic human Coronavirus in the Middle East has sparked novel concern in human coronaviruses around the world. The coronavirus came into view in Wuhan, a city of 10.9 million people in China’s Hubei zone’19. The highly contagious novel SARS-COV-2 virus not only affected the medical […]

Share this:

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X
  • BiotechToday
  • India

OUTBREAK OF ANOTHER MYSTERIOUS DISEASE IN ELURU

bioxone December 15, 2020December 15, 2020

SRILAGNA SARKAR, AMITY UNIVERSITY KOLKATA Since last Saturday night, hundreds have flooded to hospitals of Andhra Pradesh due to a sudden outbreak of a mysterious disease in Eluru city. While preliminary test report analysis has established the role of chemical substances found in pesticides the health experts are all baffled as the mystery disease has […]

Share this:

  • Click to share on Facebook (Opens in new window) Facebook
  • Click to share on X (Opens in new window) X

Breaking News

The Corrosion Prediction from the Corrosion Product Performance

Nitrogen Resilience in Waterlogged Soybean plants

Cell Senescence in Type II Diabetes: Therapeutic Potential

Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP

AI Literacy in Early Childhood Education: Challenges and Opportunities

Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

Exogenous Klotho as a Cognition Booster in Aging Primates

Terms and Conditions
Shipping and Delivery Policy
Cancellation and Refund Policy
Contact Us
Privacy Policy