–Prama Ghosh, Amity University Kolkata
A study by the University of Bristol describes a newfound mechanism of learning in the brain which stabilizes memories and decreases impedance between them.
Memories are created by excitatory connections between the nerve cells in the hypothalamus of the brain – a region crucial for the formation of memories. Inhibitory connections which dampen neuron activity balances these excitatory connections and are essential for a healthy brain.
With the help of computational modeling, the study, published in Nature Communications, for the very first time, demonstrated how two distinct types of inhibitory associations (from parvalbumin and somatostatin communicating neurons) can likewise fluctuate and increase their strength, much the same as excitatory associations. This explains why even after experiencing something new, old memories persist and remain stable.
In the near future, individual recollections of the COVID-19 pandemic are probably going to be carved in our brains with exactness and clearness, particularly from other recollections of 2020. UKRI’s Biotechnology and Biological Sciences Research Council funded the study.
Source:
Reference: “Interneuron-specific plasticity at parvalbumin and somatostatin inhibitory synapses onto CA1 pyramidal neurons shapes hippocampal output” by Matt Udakis, Victor Pedrosa, Sophie E. L. Chamberlain, Claudia Clopath and Jack R. Mellor, 2 September 2020, Nature Communications.
DOI: 10.1038/s41467-020-18074-8
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