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Category: World

Weekly Biotech News of The World

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CRISPR-Based Strategy for imaging Extrachromosomal DNA in live tumour cells

bioxone October 26, 2020October 25, 2020

Chitra Roy, University of Calcutta In 1965, a group of British oncologists viewed DNA fragments which were floating around chromosomes in cancer cells. For decades, there has been largely ignored as cellular debris. Recent advancements of technology in the field of genetics and cellular biology has paved a way for better understanding of complex diseases […]

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Is hypergastrinemia risking gastric adenocarcinoma?

bioxone October 26, 2020October 25, 2020

Arjama Roy, Amity University Kolkata Gastric adenocarcinoma is the 5th most typical cancer worldwide. The main risk factor for non-cardia gastric adenocarcinoma is atrophic gastritis. It is because of infection with Helicobacter pylori (H pylori). However, in Western populations, due to the decreasing pervasiveness of H pylori infections, the incidence of gastric adenocarcinoma has declined […]

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Should you trust ePCR over conventional PCR?

bioxone October 25, 2020October 25, 2020

Parnad Basu, Amity University Kolkata PCR (Polymerase Chain Reaction) is a technique used to amplify small segments of any DNA. In conventional PCR, DNA libraries suffer from template mispairing. This ultimately leads to the obvious loss of unique sequences. To be more efficient, ePCR (emulsion Polymerase Chain Reaction) can be used as it has a […]

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Genetic instability in Estrogen-exposed ovarian epithelium in association with ovarian cancer

bioxone October 25, 2020October 25, 2020

PRAGYA SANTRA, AMITY UNIVERSITY KOLKATA Loss of genomic stability prejudice genomic consistency, genetic makeup, and promote malignancies. Pathological mutations of DNA repair genes result in ovarian-cancer (OvCa). The elevation of damage burden proportionates to the elevated estrogen level, inducing DNA lesions that are dependent on the expression of hormone-receptors in G1, G2, and S phase. […]

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DO COVID-19 PATIENTS BENEFIT FROM TOCILIZUMAB AT ALL?

bioxone October 25, 2020October 25, 2020

Arpan Banerjee, University of Calcutta Since the time Covid-19 has plagued the entire world, many studies have evolved emphasizing its heterogeneous clinical presentation, ranging from silent asymptomatic carriers to the severe ones bogged down with respiratory failure. The clinical trials about the finding of the wonder drug is still awaited. In the meantime, several drugs […]

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Prediction of Survival Odds in COVID-19 by Zinc, Age and Selenoprotein P as Composite Biomarker

bioxone October 25, 2020October 24, 2020

Poushalee Dey, Presidency University, Kolkata Zinc is one of the most important essential trace minerals in the human body. Its deficiency causes hypozincemia. Previously, some studies reported the positive effects of zinc and selenium supplements in the prevention and treatment of viral infections. A recent study evaluated the hypothesis of zinc and selenium deficiency in […]

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Can SARS-Cov-2 be neutralized potently, using engineered ACE2 receptor traps?

bioxone October 24, 2020October 24, 2020

Ayooshi Mitra, Amity University, Kolkata The crucial mechanism for severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) and severe acute respiratory syndrome coronavirus 2  (SARS-CoV-2) infections initializes with the binding of the viral spike protein to angiotensin-converting enzyme II (ACE2) human receptor protein. In order to create a set of ACE2 variants optimized for affinity and […]

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Intravenous Tocilizumab Therapy can tackle Cytokine Storm in COVID-19 patients

bioxone October 24, 2020October 24, 2020

Chitra Roy, University of Calcutta Since its emergence, COVID-19 has been constantly challenging the medical health system across the globe. COVID-19 infection is primarily accompanied by the aggressive inflammatory response with the release of excessive amounts of pro-inflammatory cytokines which are called ‘Cytokine Storm’. The immune response of the host to SARS-CoV-2 virus is extremely […]

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Blood glucose regulation by an organ-based multi-level model

bioxone October 24, 2020October 24, 2020 6

Husna, Amity University Kolkata The process of regulation of glucose in our blood at a steady-state is known as glucose homeostasis. This regulation is very important as long-lasting disturbances in the blood sugar concentration can cause both type 1 and type 2 diabetes mellitus (T2D) and other fatal diseases. To understand this complexity of blood […]

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Structural and Functional Inhibition of CHIKV by CHK-124 and CHK-263mAbs

bioxone October 24, 2020October 23, 2020

Souradip Mallick, National Institute of Technology, Rourkela Chikungunya fever is a self-remitting viral illness that is common in tropical countries like Africa and Southeast Asia caused by the Chikungunya virus (CHIKV) (Genus- alphavirus, Family-Togaviridae), single-stranded positive-sense RNA enveloped virus, transmitted to humans by infected Aedes aegypti and Aedes albopictus mosquitoes. International travel is one of the […]

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Breaking News

The Corrosion Prediction from the Corrosion Product Performance

Nitrogen Resilience in Waterlogged Soybean plants

Cell Senescence in Type II Diabetes: Therapeutic Potential

Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP

AI Literacy in Early Childhood Education: Challenges and Opportunities

Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

Exogenous Klotho as a Cognition Booster in Aging Primates

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