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Saakshi Bangera, DY Patil School of Biotechnology and Bioinformatics RNA splicing is one of the most important processes of generating discrepancy in the transcriptome and is of utmost importance to humans. Errors in the regulation of RNA splicing lead to a wide range of genetic diseases, specifically caused by genetic mutations. RNA sequencing techniques have […]
Mustafa Vora, DY Patil University Navi Mumbai Scientists have recently discovered two types of novel brain cells that are found to be glial cells. One of them is called a gordita, which is an astrocyte, a type of glial cells. The name ‘gorditas’ comes from the plum-shaped appearance of the squat and round cell bodies. […]
Sumedha B S, Bangalore University Long-read sequencing (LRS), also called third-generation sequencing, offers a number of advantages over short-read sequencing such as Illumina’s NovaSeq, NextSeq, HiSeq and MiSeq instruments. Long-read sequencing technologies could permit the assembly of genomes, which is capable of revolutionizing genomics. It has the potential to reveal the full spectrum of human […]
Avani Dave, Jai Hind College Extracorporeal membrane oxygenation (ECMO) acts as an artificial set of the heart and lungs, allowing a patient’s respiratory foundation to rest while proceeding towards a hopeful recovery. This mechanism has been put in a good word for, particularly during the two consecutive and rampant waves of the COVID-19 pandemic. ECMO […]
Saptaparna Dasgupta, Bennett University Nucleic acids have been known to be the fundamental molecules for passing on genetic information from the parents to offspring since 1944. The recent discovery of etheno adducts of nucleic acids has opened up to new dimensions in the field of biochemical studies. Etheno adducts of nucleic acids have a 5-membered […]
Aqsa, Jamia Millia Islamia A nucleosome is a DNA segment of 147-bp coiled around a histone octamer. Each histone octamer is made up of two copies of each of the histone proteins H2A, H2B, H3, and H4. It is the fundamental subunit of chromatin. Although it seems that the nucleosome has its significance only in […]
Shayan Ahmed, Jamia Millia Islamia, New Delhi Antibiotic resistance happens to be an important phenomenon emerging as a defence mechanism in bacteria. Antibiotic resistance mechanisms are the reason bacteria are able to counter the effects of antibiotics. Immeasurable and indiscriminate use of antibiotics ever since their discovery has contributed to the development of antibiotic resistance. […]
Saptaparna Pal, Amity University Kolkata The ATP binding cassette (ABC) transporter ABCG2, also known as breast cancer resistance protein is expressed in many tissues and tissue barriers, including blood-brain, blood-testis, and maternal-fetal barriers. It transports endogenous substrates such as estrone 3-sulfate and uric acid and also removes cytotoxic and endogenous compounds from cells. ABCG2 actively […]
Kanikah Mehndiratta Transcriptomic analysis has been a recent approach to identify biomarkers associated with normal or diseased physiology in patients. An obvious approach to targeting any infection or disease through treatment strategies or prophylaxis requires a proper understanding of the mechanisms of its pathogenesis. Researching on better and more effective treatment approaches towards a deadly […]
Akash Singh, Banaras Hindu University Autophagy, often blamed for senescence, is a conserved process that promotes cellular homeostasis by degrading cytosolic components (sometimes referred to as cargo). This cargo sequestered into autophagosomes, which are double-membrane vesicles that are primarily carried in the retrograde direction to the perinuclear area, where they combine with lysosomes, ensuring cargo […]
