News
Camelia Bhattacharyya, Amity University Kolkata The pandemic, that is, the COVID-19 pandemic hit the world all of a sudden, changing infection rates or rather increasing it every day without leaving the world to think of the ways to fight with the unknown enemy, the virus. This created a lot of panic at the beginning of […]
Rohit Bhattacharjee, Amity University Kolkata Acyl CoA synthetase 4 (ACSL4) is an isoenzyme of the fatty acid ligase-coenzyme A family that takes part in arachidonic acid metabolism and steroidogenesis. ACSL4 is involved in tumour aggressiveness in breast and prostate tumours through various signal transduction pathways regulation. A well-validated ACSL4 inhibitor, however, has not been reported […]
Surupa Chakraborty, Amity University Kolkata The U.S. Food and Drug Administration recently approved Inmazeb, a potent treatment involving a cocktail of three lab-made monoclonal antibodies (atoltivimab, maftivimab, and odesivimab-ebgn) to fight against Ebola, one of the world’s deadliest diseases known so far. Inmazeb targets the glycoprotein, which latches onto the cell surface receptors and fuses […]
Aakancha Shaw, St. Xavier’s College, Kolkata Humic acid (HA) is a natural, organic compound that is derived from plant and animal residues. It was observed that on combining it with the phosphate-based fertilizers, the efficiency of the fertilizer for plants was enhanced. Since then, humic acid supplements have been used to increase the efficiency of […]
Saptaparna Pal, Amity University Kolkata Bacterial messenger RNA (mRNA) sequencing gives a snapshot of the genomic wide state of microbial population and hence provides a fundamental understanding of these varied phenotypes and microbial functions. Entire RNA isolated from the bacterial cells contains greater than 95% ribosomal RNA, and therefore it is cost-effective and high coverage […]
Aishila Kar, Amity University Kolkata Malaria is the deadliest vector-borne disease worldwide with an average of 228 million cases, and 405,000 deaths in 2018, mainly in the African Region (93%), and the South-East Asia Region (3.4%). In Laos, the malaria burden remains despite a significant reduction of cases during the last decade. In the condition […]
Chitra Roy, University of Calcutta High-Grade Serous Ovarian Carcinoma (HGSOC) is one of the most common and deadliest types of ovarian cancer. This gynaecological malignancy is a type of tumour which arises from the ovary, fallopian tube, or peritoneum. The tumour microenvironment is very complex and 40% of this tumour mass contains Macrophages. Macrophages originate […]
Husna, Amity University Kolkata Proton pump inhibitors (PPIs) are a class of medicines that work on the cells which are lining the stomach, reducing the production of acid in our stomach. They can treat heartburn and gastric acid reflux by irreversibly binding with the Na+ H+ ATPase located on the surface of gastric parietal cells.PPIs […]
Devyani Goswami, Amity University Kolkata SADS-CoV (Swine acute diarrhoea syndrome coronavirus), transmitted through the faeces of horseshoe bat to pigs. Majorly affecting the piglets, with death in 90% of the cases within 5 days. The major symptoms include diarrhoea and vomiting. SADS-CoV was identified first in 2004 and 2006 in the bats. First clinical signs […]
Prama Ghosh, Amity University Kolkata Sepsis, a complication caused by dysregulation of the immune system causes around 11 million deaths every year in the world. Treatment includes antibiotics and organ support measures, but it fails many times due to unsuccessful attempts at modulating the immune response. Surviving the condition requires activation of resistance mechanisms which […]
