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PRAGYA SANTRA, AMITY UNIVERSITY KOLKATA Loss of genomic stability prejudice genomic consistency, genetic makeup, and promote malignancies. Pathological mutations of DNA repair genes result in ovarian-cancer (OvCa). The elevation of damage burden proportionates to the elevated estrogen level, inducing DNA lesions that are dependent on the expression of hormone-receptors in G1, G2, and S phase. […]
Arpan Banerjee, University of Calcutta Since the time Covid-19 has plagued the entire world, many studies have evolved emphasizing its heterogeneous clinical presentation, ranging from silent asymptomatic carriers to the severe ones bogged down with respiratory failure. The clinical trials about the finding of the wonder drug is still awaited. In the meantime, several drugs […]
Poushalee Dey, Presidency University, Kolkata Zinc is one of the most important essential trace minerals in the human body. Its deficiency causes hypozincemia. Previously, some studies reported the positive effects of zinc and selenium supplements in the prevention and treatment of viral infections. A recent study evaluated the hypothesis of zinc and selenium deficiency in […]
Ayooshi Mitra, Amity University, Kolkata The crucial mechanism for severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections initializes with the binding of the viral spike protein to angiotensin-converting enzyme II (ACE2) human receptor protein. In order to create a set of ACE2 variants optimized for affinity and […]
Chitra Roy, University of Calcutta Since its emergence, COVID-19 has been constantly challenging the medical health system across the globe. COVID-19 infection is primarily accompanied by the aggressive inflammatory response with the release of excessive amounts of pro-inflammatory cytokines which are called ‘Cytokine Storm’. The immune response of the host to SARS-CoV-2 virus is extremely […]
Husna, Amity University Kolkata The process of regulation of glucose in our blood at a steady-state is known as glucose homeostasis. This regulation is very important as long-lasting disturbances in the blood sugar concentration can cause both type 1 and type 2 diabetes mellitus (T2D) and other fatal diseases. To understand this complexity of blood […]
Souradip Mallick, National Institute of Technology, Rourkela Chikungunya fever is a self-remitting viral illness that is common in tropical countries like Africa and Southeast Asia caused by the Chikungunya virus (CHIKV) (Genus- alphavirus, Family-Togaviridae), single-stranded positive-sense RNA enveloped virus, transmitted to humans by infected Aedes aegypti and Aedes albopictus mosquitoes. International travel is one of the […]
Shreelekha Pore, National Institute of Technology, Rourkela 25% of non-Hodgkin Lymphoma includes Diffuse Large B-Cell Lymphoma (DLBCL). Through the study of cell-of-origin (COO) using gene expression profiling (GEP), DLBCL has been classified as- germinal centre B-cell-like and activated B-cell-like. Artificial intelligence is widely used for prognostic purposes for certain diseases. Machine Learning can be used […]
Jayateerth S. Bhavikatti, CSIR-National Chemical Laboratory, Pune, India There have been so many things discovered till date in this universe, nevertheless, there are too many discoveries to happen. Cheers to the discoverers! They spend their life helping people. Here is one such discovery. So far, three pairs of salivary glands were studied in humans. Researches […]
-Sashreek Ganguli, Amity University Kolkata One- fifth of the COVID-19 patients in today’s world develop critical interstitial pneumonia characterized by bilateral interstitial infiltrates, leading to Acute Respiratory Distress Syndrome (ARDS) and respiratory failure. These patients while under treatment show acute hypoxemia and often have persistent dyspnea, despite the administration of oxygen flows>10–15l/min through a facial […]
