-Team bioXone
Research by an international team of scientists suggested that regular use of proton pump inhibitors (PPIs), commonly used to treat acid reflux, are related to a heightened risk of developing type 2 diabetes. The results also indicated that with the duration of PPI use, this risk of type 2 diabetes increases; prompting the researchers to advise people who take these drugs for more than 2 years should do regular blood glucose check-ups to be alert from diabetes.
PPIs are commonly used worldwide to treat peptic ulcers, acid reflux, and indigestion. While it is generally accepted that usage of PPIs for the short term is safe, yet long-term usage has been linked to an increased risk of chronic kidney disease, bone fractures, and stomach cancer. Recent studies also indicated that PPIs could affect gut microbes.
In deep-analysis showed that diabetes risk among PPI users wasn’t affected by age, sex, smoking, alcohol intake, family history of diabetes, high cholesterol, diet, physical activity, or regular use of anti-inflammatory drugs. But it was found higher among participants who were not overweight and had normal blood pressure.
A good amount of evidence suggests that alterations in the type/ volume of bacteria in the gut (the microbiome) may help explain the linkage found between PPI use and an increased risk of developing diabetes.
Scientists conclude that the varied range of side effects also with the heightened risk of diabetes is made to be cured by prescribing PPI drugs; in any case, clinical practitioners should carefully assess the pros and cons before prescribing any related PPI medication.
Phylloid-type pigmentary | mosaicism and ambiguous genitalia | trisomy 14 | der(Y)t(Y;14)
-Husna, Amity University Kolkata Trisomy 14 is an aneusomy that is viable with life if present in a mosaic individual. Mostly, the symptoms are prenatal and postnatal growth failure, genitourinary and ear abnormalities, congenital heart defects, developmental delay, narrow palpebral fissures, broad nose, short jaw, and short neck. A clinical survey on 51 patients showed […]