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  • First-line treatment counter to Sunitinib (RTKi) for metastatic kidney cancer

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Can E.coli combat ionizing radiation?

First-line treatment counter to Sunitinib (RTKi) for metastatic kidney cancer
  • World

First-line treatment counter to Sunitinib (RTKi) for metastatic kidney cancer

bioxone September 22, 2020September 22, 2020

Sambit Majumdar, Amity University Kolkata

Metastatic cancer is a sort of cancer that spread to different parts of the body from where it’s started. Metastatic kidney cancer often spreads to the lungs, brain, bones, and other parts of the body. The 3 CheckMate 9ER trial has provided a first-line treatment for patients with this sort of cancer.

A recent treatment trial is published by the European Society of Medical Oncology (ESMO), during which they used two sorts of the drug for trials as mono-therapies within the second line nivolumab and cabozantinib and combined them to be used as a first-line treatment counter to sunitinib. The compound came intent on loftier in the survival of the patient without getting worse. This has received a stronger repose rate in various age groups, sex, PD-L1 expression, and IMDC risk group.

The Director of Dana-Farber Cancer Institute and also the Jerome and Nancy Kohlberg Chair and Professor of medication, Harvard School of medicine, Boston, USA said that the results with this compound therapy were statistically significant and clinically meaningful and risk of progression and death was almost cut by 50% and 40% respectively, and also the response rate doubled.

Suggested Report:

https://medicalxpress.com/news/2020-09-first-line-treatment-option-metastatic-kidney.html

Paper to Read: https://pubmed.ncbi.nlm.nih.gov/30173085/

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Can E.coli combat ionizing radiation?

bioxone September 23, 2020

-Anuska Sen,Team bioXone Ionizing radiation (IR) is known to have numerous ill-effects and can even be fatal to most organisms on exposure at high concentrations. Scientists are continuously in search of organisms or strains of bacteria that are resistant to such radiation, meaning which possess the property of “radio-resistance”. Till date, it was known that […]

ionizing radiation

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Butterflies need cool shades to survive!

bioxone September 26, 2020September 26, 2020

Richismita Hazra, Amity University Kolkata Climatic variations affect the abundance, spread, and phenology of species. Removal of microclimates that the butterflies need to survive, along with drastic climatic variations has led to extreme weather alterations and temperature fluctuations. This has affected the survival of butterflies that are ectotherms and hence dependent on external sources of […]

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Do lncRNA MCM3AP-AS1 develop lung cancer?

bioxone July 20, 2021July 19, 2021

Monika Raman, PSG College of Technology, Coimbatore Lung cancer, one of the most common and deadliest cancers, affected 2.2 million people and caused 1.79 million deaths worldwide in 2020. Most of the primary lung cancers are carcinomas. Small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC) are their two main types.  About 15% of lung […]

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COMPUTER DESIGNED SYNTHETIC ANTIVIRAL PROTEINS INHIBIT SARS-COV 2/COVID 19 IN HUMAN CELLS

bioxone September 15, 2020September 15, 2020

–Rishav Chakraborty, Calcutta National Medical College, Kolkata The SARS-COV infection occurred first in 2003-2004. The infection is believed to be contracted from animals including monkeys, Himalayan palm civets, cats, dogs, and rodents. Clinical manifestation including myalgia, headache, sore throat, and fever followed by severe respiratory distress. The virus binds with the ACE-2 (Angiotensinogen Converting Enzyme) […]

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Breaking News

The Corrosion Prediction from the Corrosion Product Performance

Nitrogen Resilience in Waterlogged Soybean plants

Cell Senescence in Type II Diabetes: Therapeutic Potential

Transgene-Free Canker-Resistant Citrus sinensis with Cas12/RNP

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Sustainable Methanol Vapor Sensor Made with Molecularly Imprinted Polymer

Exogenous Klotho as a Cognition Booster in Aging Primates

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